LKB1 Is an Essential Regulator of Spermatozoa Release during Spermiation in the Mammalian Testis
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LKB1 Is an Essential Regulator of Spermatozoa Release during Spermiation in the Mammalian Testis
LKB1 acts as a master upstream protein kinase regulating a number of kinases involved in diverse cellular functions. Recent studies have suggested a role for LKB1 in male fertility. Male mice with reduced total LKB1 expression, including the complete absence of the major splice variant in testis (LKB1(S)), are completely infertile. We sought to further characterise these mice and determine the ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0028306